Objective To investigate the effect of combined application of CD3mAb and retronectin on CD56+ cell proliferation and its cytolytic activity against pancreatic carcinoma cells in vitro.Methods CD56+ cells were enriched from peripheral blood mononuclear cells(PBMCs) using CD56 MACS separation system.The isolated CD56+ cells were co-incubated with CD3mAb and retronectin,the proliferation of CD56+ cells and the [...]
18
May
18
May
Metronomic paclitaxel combined with EGCG inhibits growth of gastric cancer and angiogenesis
OBJECTIVE:To evaluate the anti-angiogenic and anti-tumor effects of low-dose paclitaxel combined with(-)-epigallocatechin-3-gallate(EGCG) on gastric cancer.METHODS:Nude mice bearing BGC-823 human gastric carcinoma were randomized into five groups.The nude mice were administered by sterile saline(0.9%),maximum tolerable dose(MTD) paclitaxel,low-dose paclitaxel,EGCG and low-dose paclitaxel combined with EGCG,respectively.Tumor growth was monitored in each group.Expression of microvessel density(MVD) and VEGF was [...]
18
May
89 cases of Adenocarcinoma of the Breast Clinical and Pathologic Analysis
Objective:Adenocarcinoma of the breast clinical and pathological analysis.MethodS:89cases of adenocarcinoma of the breast to surgery,the consolidation of chemotherapy,radiotherapy and endocrine therapy.Results:The pathological tumor pathology,simply type adenocarcinoma of the breast in 48cases,mixed-type adenocarcinoma of the breast in 41cases,followed by 10mo-8asurvival after 5years,62cases of simple group of 36patients,5years survival rate is 76.11%groups compares P<0.05(χ2=4.124),the pure group obviously [...]
18
May
Studies on Mechanism of Lung Cancer by TCM Physique Study and Modern Medicine
The study of TCM constitution theory has made significant progress after the long period of development.Judging from the tumor,it is closely related to the pathogenesis of human body physique condition,and the development of physical biased is the important factor of tumor.The authors proposed by the constitution of TCM syndrome occurrence and development of tumor,combining modern [...]
18
May
17
May
Expression of hPH-20(hSPAM1) mRNA in prostate cancer tissue
Objective To study the expression of human sperm membrane gene hPH-20(hSPAM1)mRNA in the prostate cancer tissue.Methods The hPH-20(hSPAM1)mRNA expression in prostate cancer tissue(n=35) and normal prostate tissue(n=5) were detected by reverse transcriptase polymerase chain reaction(RT-PCR).Results The percentages of hPH-20(hSPAM1)mRNA positive expression in prostate cancer tissue were significantly higher than normal prostate tissue(P<0.05);hPH-20(hSPAM1)mRNA expression in stage [...]
17
May
The Research of the Inhibition of Cordycepin on Human Pancreatic Cell Cancer BxPc3 and Cell BxPc3-LN5
Objective To assess the inhibition of cordycepin on human pancreatic cancer cell BxPc3 and BxPc3-LN5, which is a high metastatic potential cell line from BxPc3 cell. To discuss the theory of feasibility of the clinical chemotherapy in pancreatic cancer by cordycepin. Methods MTT assay was used to examine the cordycepin-induced growth inhibition in human pancreatic [...]
17
May
Clinical Value of Color Doppler Ultrasound in the Diagnosis of Thyroid Disease
Objective To study clinical value of the color Doppler ultrasound in the diagnosis of thyroid disease Methods All 132 cases patients with thyroid disease with color Doppler ultrasound examination From January 2006 to June 2010 were analyzed such as thyroid adenoma, thyroid cystadenoma, nodular goiter, thyroid cancer, hyperthyroidism, subacute thyroiditis, Hashimoto’s thyroiditis performance and CDFI [...]
17
May
Influencing Factors of Primary Cytoreduction and Prognostic Factors in Advanced Epithelial Ovarian Cancer
Objective:To study the prognosis and factors affecting primary cytoreduction in advanced epithelial ovarian cancer.Methods:111 cases of advanced epithelial ovarian cancer admitted in our hospital for primary cytoreduction from 2003 to 2007 were retrospectively analyzed by SPSS11.5 software.Results:In advanced ovarian cancer 3-year survival rates and 5-year survival rates were 37.8% and 11.7% respectively.Univariate analysis showed that [...]
17
May
Efficacy of Three Chemotherapy Regimens for Advanced Esophageal Cancers
Objective To evaluate therapeutic efficiency,safety of paclitaxel(PTX)/nedaplatin(NDP) and paclitaxel(PTX)/cisplatin(DDP) therapy for patients with advanced esophageal cancers.Methods One hundred and thirty five patients with advanced esophageal cancers were analyzed.Group PTX+NDP:composed 44 cases,patients in PTX/NDP group were given PTX 150 mg/m2 on d1 and NDP 20 mg/m2 from d2 to d5.Group PTX+DDP:composed 46 cases,patients in PTX/DDP group [...]