【Objective】 To investigate the serum pepsinogen(PG) changes in the gastric diseases.【Methods】 245 patients were selected in the study including 53 cases of non-atrophic gastritis,20 cases of chronic atrophic gastritis,36 cases of gastric ulcer,31 cases of duodenal ulcer,69 cases of advanced gastric cancer,13 cases of early gastric cancer and 23 cases of gastrectomy for gastric cancer [...]
18
May
18
May
23 cases of continous ambulatory peritoneal dialysis patients withdrew from dialysis reasons
Objective To analyze 23 cases of continuous ambulatory peritoneal dialysis(CAPD)patients withdrew from dialysis reasons.Methods Analyzed of Jinshan,Shanghai Sixth People’s Hospital branch from January 2007 to December 2010 60 cases of CAPD ≥ 3 during the month of peritoneal dialysis patients the reasons for withdrawal.Results A total of 23 patients out peritoneal dialysis peritoneal dialysis the [...]
18
May
Role of artesunate in resistance-reversal of esophageal cancer Eca109/ADM cells to doxorubicin
Objective: To explore the role of artesunate(Art) in resistance-reversal of Eca109/ADM cells and the related mechanism.Methods:The present study was divided into 4 groups: normal saline(NS) control group,Art(0.1 μmol/L) group,ADM(0.2 μg/ml) group,and Art(0.1 μmol/L)+ADM(0.2 μg/ml) group.The apoptosis rate,ADM content and ABCG2(ATP-binding cassette transporter G2) protein expression in Eca109/ADM cells were detected by flow cytometry 48 h [...]
18
May
Effect of JNK signaling pathway inhibition on TRAIL-induced apoptosis in human gastric cancer cells
OBJECTIVE:To investigate the effect of JNK signaling pathway on TRAIL-induced apoptosis in human gastric cancer cells.METHODS:Methyl thiazolyl tetrazolium(MTT) assay was used to determine the cell viability;Western blotting was used to detect the levels of phosphor-JNK and total JNK;Flow cytometry following Propidium Iodide(PI) staining was used to determine the apoptosis as well as cell cycle distribution.The [...]
18
May
18
May
Analysis on the activity of HK,PK and the test of lactate content in pancreatic carcinoma tissue
Objective To test the activity of hexokinase(HK),pyruvate kinase(PK) and the lactate content in pancreatic carcinoma tissue,and to explore the relation between biological behavior of pancreatic cancer and glycolysis.Methods We collected the tissue samples from 21 cases of pancreatic adenocarcinoma and 11 cases of benign lesions such as insulinoma.The total activity of HK,PK and the content [...]
18
May
The Competition of Sulfur and Selinium and Their Effection on Health Care Function in Broccoli:A Review
Broccoli is a cruciferae vegetable which riches in sulforaphane and selenium(Se).Lots of studies demostrate that sulforaphane or Se can reduce cancer risk.Recent research showed that Se have competitive effect with sulfur.But sulfur is an essential component for sulforaphane,so it would reduce the sulforaphane content when plant uptake Se.However,sulforaphance and Se has synergistic effect in cancer [...]
18
May
Nursing Intervention for lung Cancer Ppatients with Negative Psychological Impact
Objective:To understand the lung cancer patients during chemotherapy psychological reactions of nursing interventions.Methods:A self-rating anxiety scale(SAD)and the self-rating depression scale(SDS)of 200patients with lung cancer during chemotherapy of experimental group were based on the general psychological care,a more comprehensive psychological intervention program.Results:The patients with anxiety and depression symptoms was significantly lower than the control group P<0.01(χ2=19.315,8.149).Conclusion:The [...]
17
May
Study on Mechanism of Low Expression of Tumor Suppressor Gene DLC-1 in Human Breast Cancer Cell Line
Objective:To investigate the mechanism of low expression of tumor suppressor gene dlc-1 in human breast cancer cell line.Methods:Methylation-specific PCP(MSP) was used to examine the methylation status of DLC-1 promoter.MCF-7 cells were treated by different concentrations of 5-Aza-CdR.DLC-1 mRNA levels were examined by RT-PCR and Real-time PCR before and after treatment with 5-Aza-CdR.Results:There was methylation in [...]
17
May
Contrastive clinical study of conservative and modified radical mastectomy for early breast cancer
Objective: To compare the prognostic influence of conservative mastectomy and modified radical mastectomy on patients with early breast cancer.Methods: Retrospectively analyzed 63 subjects for conservative Mastectomy in early breast cancer of our hospital between July 2005 to July 2008,and to contrastively investigated with 63 subjects for modified radical mastectomy in early breast cancer on the [...]