[Objective]To evaluate the oral complications of cancer patients after chemotherapy and the clinical efficacy of control measures.[Methods]During the May 2007-May 2010,326 cases with various oral complications after chemotherapy were treated by different control measures in our hospital,including 152 patients with oral mucositis,93 cases with oral infection,81 cases with xerostomia and the control effect was valuated.[Results]2 [...]
18
May
18
May
Inhibitory effect of RNA interference targeting hTERT gene of Hela cells
Objective To explore the inhibitory effect of RNA interference(RNAi) targeting human telomerase reverse transcriptase(hTERT) gene of cervical carcinoma Hela cells.Methods Small interfering RNAs(siRNAs) targeting hTERT gene was synthesized with chemical technique,and siRNAs were transfected into Hela cells by cationic lipofection.Cervical carcinoma Hela cells were divided into six groups,blank group(untransfected Hela cells group),negative group(negative control siRNA [...]
18
May
Analysis on the effects of psychological intervention on low rectal cancer patients during treatment
Objective:analyze the effects of psychological intervention on rectal cancer patients during treatment and investigate their clinical significance.Methods:We selected 274 patients who divided into two groups:the trial group 137 cases with psychological intervention and the control groups 137 cases without psychological intervention.Then the survey for the psychological problems was performed with the use of symptom checklist [...]
18
May
18
May
Dosimetric study of coplanar decile intensity-modulated radiotherapy and 3-dimensional conformal radiotherapy for postoperative rectal cancer
OBJECTIVE:To compare the difference of dose distribution in clinical target volume and organ at risk(OAR) and other economic indicators between coplanar decile field intensity-modulated radiotherapy(IMRT) and conventional three-dimensional conformal radiotherapy(3D-CRT) in the radiotherapy of rectal cancer.METHODS:Sixteen patients with rectal cancer treated with postoperative radiotherapy(RT) were retrospectively analyzed.Eight were male and eight were female.The target volume [...]
18
May
Large Doses of BOP(N-nitrosobis(2-oxopropyl)amine) Induced Intrahepatic Cholangiocarcinoma Rather than Pancreatic Cancer in Golden Hamsters
Objective: To establish a golden hamster model of pancreatic cancer using a large dosage of BOP(N-nitrosobis(2-oxopropyl)amine).Methods: BOP was administered(s.c.) to 48 female golden hamsters(body weights 91-109 g) at the doses(5 weekly doses: the first,70 mg/kg bodyweight,and the remaining,20 mg/kg) as used in the literature(Cancer Res,2006,66,4503-11).8 weeks later,the animals(n=10) with apparent ascites were killed;12 weeks later,the [...]
17
May
Effect of the Titration of Oxycodone Controlled-release Tablets on Moderate Pain.
Objective To evaluate the efficacy advantage of oxycodone hydrochloride controlled-release tablets for moderate cancer pain.Methods This study selected 67 patients suffering from moderate pain without a history of opioid.They were randomly divided into 2 groups.A group(35 cases) used the oxycodone hydrochloride controlled-release tablets 5mg as the initial dose for titration,and B group(32 cases) used the [...]
17
May
Effect and clinical significance of survivin expression in intra-uterine arterial neoadjuvant chemotherapy for stage Ⅱ cervical carcinoma
Objective To evaluate the effects and clinical significance of survivin expression in intra-uterine arterial neoadjuvant chemotherapy for stage Ⅱ locally advanced cervical cancer.Methods Seventy-seven patients with locally advanced cervical cancer,FIGO Stage Ⅱ,from January 2005～December 2007 were enrolled in this study,those patients were primary treatment by neoadjuvant intra-uterine arterial chemotherapy.Immunohistochemistry were performed to eximine the expression [...]
17
May
The diagnosis values of MRI diffusion tensor imaging in prostate disease
Aim:To investigate the value of DTI in diagnosis and differential diagnosis of prostate cancer(PCa) and benign prostatic hyperplasia(BPH).Methods: Twenty-two patients with PCa,31 BPH patients and 20 healthy volunteers were scanned in prostate DTI.All data were transfered to the AW 4.2 workstation for processing.The changes of fractional anisotropy(FA) and average apparent diffusion coefficient(ADC) of PCa foci,BPH [...]
17
May