Objective To explore the use of surface-enhanced laser desorption/ionization time of flight mass spectrometry(SELDI-TOF-MS) technology in the differential diagnosis of pulmonary tuberculosis and lung cancer. Method The serum samples were collected from 65 tuberculosis patients and 65 lung cancer patients.Serum proteins were captured using WCX2 chips,then scanned and analyzed using chip reader PBSⅡ. Results Comparing [...]
18
May
18
May
Early Diagnosis Analysis of Primary Hepatolellular Carcinoma in Laboratory
Primary hepatocellular carcinoma(HCC)is one of the malignant tumors with the highest death cause and increasing incidence.Serum tumor marker is very important significance for early diagnosis,tumor progression monitoring,therapeutic effect evaluation,tumors recurrence and patients’survival prediction.AFP,DCP,AFU,GGT,GP73,GPC-3,SCCA,and AIF are important markers which are commonly used in clinical diagnosis of liver cancer traditionally.The above markers can diagnose the tumors in [...]
17
May
Diagnostic value of diffusion-weighted MR imaging in distinguishing benign from malignant breast lesions
Objective To investigate the value of diffusion-weighted magnetic resonance imaging in distinguishing benign from malignant breast lesions.Methods 50 cases of breast cancer patients and 50 cases of patients with benign breast lesions went to our hospital from February 2010 to August 2010 were collected.All of the lesions were confirmed by operation and pathology.Diffusion weighted imaging [...]
17
May
Application value of core needle biopsy in diagnosing breast cancer
Objective:To explore application value of core needle biopsy(CNB) in diagnosing breast cancer.Methods:297 patients with highly suspicious breast masses were performed hollow needle aspiration biopsy in which the result were contrastively analysed on the histopathology between puncture biopsy and surgical specimens.Results:There were 23 cases of benign masses including 8 cases in fibroadenoma and 15 cases in [...]
17
May
Qualitative Study on Process of Malignant Tumor Recognition and Diagnosis
Objective To understand factors related to recognition and diagnosis of malignant tumor.Methods Eighteen patients affected by cancer were performed in-depth interview.Interviews were recorded,transcribed verbatim and coded independently by two researchers.Clolaizzi method was used to form main subjects.Results During process of malignant tumor recognition and diagnosis,four main issues were abstracted.They were indication symptom or physical sign,prompting [...]
16
May
Application and Research Progress of Raman Spectroscopy Diagnosis in the Gastric Cancer
Raman spectroscopy is a molecular vibrational spectroscopic technique that is capable of optically probing the biomolecular changes associated with diseased transformation.Gastric cancer is currently the fourth most common malignancy, and also the second leading cause of cancer deaths in humans worldwide.As the possibilities in the treatment of gastric cancer continue to evolve,its early detection and [...]
16
May
Colon cancer-related microRNAs:implications for translational research
Colon carcinogenesis is a stepwise progression from polyps to adenocarcinomas and distant metastasis.These pathologic changes are contributed by aberrant activation or inactivation of protein-coding proto-oncogenes and tumor suppressor genes.However,recent discoveries in microRNA research have reshaped our understanding of the role of non-protein-coding genes in carcinogenesis.In this regard,a remarkable number of microRNAs exhibit differential expression in [...]
16
May
16
May
Surgical management of gastric stump cancer: a report of 32 cases
[Objective] To evaluate the prognostic factors of gastric stump cancer(GSC).[Methods] Clinical data of 32 GSC patients who were admitted into the surgery department of the hospital from 1999 to 2009 were analyzed in this study.All cases were diagnosed with gastroduodenoal endoscopy and CT scan.The time from the first gastrectomy to the diagnosis of the GSC [...]
16
May
Development of research on the relationship between miRNAs and breast cancer
miRNAs are endogenous,non-coding small RNAs that play an important role in the many biological processes including cell proliferation,differentiation,apoptosis and ontogeny.miRNAs can promote the occurrence and advance of the breast cancer by upregulation the expression of miRNAs in breast cancer.Detection of circulating miRNAs may become non-invasive,effective biomarkers to diagnose the breast cancer.miRNAs also related to the [...]