Objective To explore the relationship between CD133 and clinicopathological parameters by studying the CD133 expression in gastric cancer tissue.Methods RT-PCR technique and immunohistochemical method were used to detect the expression of CD133 in the fresh resected gastric cancer tissue and adjacent normal tissue of gastric cancer from 33 cases.Results The relative gray value of CD133 [...]
18
May
18
May
Research on Abnormal Methylation of DAPK1 Gene in Human Gastric Cancer
Objective To study the situation of DAPK1 gene methylation and the expression of DAPK1 in human gatric cancer tissues.Methods The methylation of DAPK1 was detected by MSP,and the expression of DAPK1 was detected by RT-PCR.Results The low expression of DAPK1′s mRNA is 16/35(P=0.465).The rate of DAPK1 gene methylation in human gastric cancer tissues and cancer-adjacent [...]
18
May
IL-2 Expression in Early Gastric Cancer Patients and Normal Healthy Human Serum
Objective To investigate the gastric cancer patients and healthy controls serum IL-2 levels in.Methods Select the initial hospitalization were 26 cases of early gastric cancer patients included in clinical studies of this item.All subjects were collected and separated serum samples,ELISA to detect serum IL-2levels.Results Early gastric cancer in patients with IL-2 levels than normal,healthy people [...]
18
May
18
May
Risk Factors for Gastric Cancer in Tianjin Area: A Case-control Study
Objective To understand the risk factors for gastric cancer in Tianjin area.Methods 100 patients,all pathologically diagnosed as gastric cancer by way of gastroscopy or surgery,and 109 cases of chronic superficial gastritis or chronic atrophic gastritis,all gastroscopically diagnosed at the same period,were selected and investigated by questionnaire.The data was analyzed by Logistic regression method.Results The results [...]
17
May
Nursing intervention on cancer recovery period of surgical anesthesia
Objective:To analyze the nursing intervention on cancer recovery period of surgical anesthesia.Methods:In January 2008 January-2010 anesthesia in our hospital patients radical gastrectomy 70 patients were randomly divided into control group and observation group,35 patients each.The control group do not do special intervention of the operating room temperature,the observation group for patients covered insulation blanket,liquid heaters,electric [...]
17
May
A Preliminary Study of Endostar Combined with Chemotherapy on Advanced Gastric Cancer
Objective To investigate the effect of rh-endostar injection combined with OLF chemotherapy on quality of life and survival period in postoperative patients with advanced gastric cancer. Methods Sixty-eight patients with advanced gastric cancer were divided into two groups:OLF group was(34 cases)treated with oxaliplatin 130mg/m2, d1;leucovorin 200mg/m2, d1-5; 5-FU 400mg/m2 iv d1-5 every 21 days for [...]
17
May
The Research Status of Treating Gastric Cancer with Traditional Chinese Medicine of Strengthening Spleen and Warding off Disaster
By analyzing related literature the main pathogenesis was the weak of spleen and stomach,the treatment with traditional chinese medicine of strengthening spleen and warding off disaster can improve symptoms after surgery,reduce side effects of chemotherapy,anti-recurrence,metastasis and improve immune function.
17
May
Demethylation of CHFR gene in gastric cancer cell line AGS by 5-Aza-CdR and its clinical applications
Objective To explore demethylation effect of 5-Aza-2′deoxycytidine(5-Aza-CdR)in gastric cancer cell line AGS and study its clinical applications.Methods Bisulfite sequencing PCR(BSP) and reverse transcriptase PCR(RT-PCR) were used to detect CHFR gene promoter′s methylation status and its mRNA expression pre and post 5-Aza-CdR treatment in gastric cancer cell line AGS respectively.Results CHFR gene promoter displayed hypermethylated in [...]
17
May
Inhibition effect and mechanism of 5-Aza-CdR on proliferation and apoptosis in gastric cancer cell line AGS
Objective To study the inhibition effect of 5-Aza-2′deoxycytidine(5-Aza-CdR) on proliferation and apoptosis of gastric cancer cell line AGS and explore its possible mechanisms.Methods Low,median and high concentrations of 5-Aza-CdR were used to treat gastric cancer cell line AGS.Cell counting kit-8 was employed to detect the proliferation of gastric cancer cell line AGS;flow cytometer was used [...]