Date

Cancer Research Center

Research on Cancer Causes, Cancer Treatment for Breast, Lung, Skin, Lymphoma, Leukemia and other Cancer Types
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Expression and translocation of targeted antigen of anti-lung cancer 15A1 monoclonal antibody in lung cancer cells

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Objective: To study the expression,subcellular localization and translocation of the targeted antigen of anti-lung cancer 15A1 mAb in lung cancer cells,and to study the inhibitory function of 15A1 mAb in vitro and in vivo against lung cancer cells,so as to provide target and antibody drug candidate for targeted therapy of lung cancer.Methods: The expression and [...]

Nursing Intervention for lung Cancer Ppatients with Negative Psychological Impact

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Objective:To understand the lung cancer patients during chemotherapy psychological reactions of nursing interventions.Methods:A self-rating anxiety scale(SAD)and the self-rating depression scale(SDS)of 200patients with lung cancer during chemotherapy of experimental group were based on the general psychological care,a more comprehensive psychological intervention program.Results:The patients with anxiety and depression symptoms was significantly lower than the control group P<0.01(χ2=19.315,8.149).Conclusion:The [...]

Studies on Mechanism of Lung Cancer by TCM Physique Study and Modern Medicine

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The study of TCM constitution theory has made significant progress after the long period of development.Judging from the tumor,it is closely related to the pathogenesis of human body physique condition,and the development of physical biased is the important factor of tumor.The authors proposed by the constitution of TCM syndrome occurrence and development of tumor,combining modern [...]

Replacement of Superior Vena Cava in the Treatment of Chest Tumor

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Objective To evaluate and summarize the clinical experience of the vessel resection and reconstruction in surgical management of malignant superior vena cava syndrome(SVCS).Methods Five patients with SVC being invaded by tumors were included and analyzed retrospectively in this study.Among them locally advanced lung cancer was in three cases,invasive thymoma in two cases.The primary tumor was [...]

Application of Plan Replant Technique to Boost Radiotherapy of Lung Cancer

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Objective To discuss application of plan replant technique to boost radiotherapy of lung cancer.Methods Six patients with lung cancer,who underwent boost radiotherapy in our hospital,were chosen in the present study.The first radiotherapy plans were replanted to the second CT-scan images and new plans were obtained.The dose in the relative important organs in new plans was [...]

The clinical values of serum tumor markers levels in lung cancer patients at different stages

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Objective:To research the correlation between serum tumor markers levels and stagging of lung cancer in patients with terminal lung cancer.Methods:Staging of 48 patients with terminal lung cancer were diagnosed.The serum tumor markers levels of CEA,NSE,CYFRA21-1 and CA125 were determined,and analyzed the correlation between serum tumor markers levels and lung cancer in patients with terminal lung [...]

Research Progress of Tumor Markers in Early Diagnosis of Lung Cancer

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Lung cancer is one of the most prevalently occurring,both its incidence and fatality rate are the highest among all cancers. Some ongoing diagnostic tools at clinics include CT scans,bronchoscopy,tumor markers and sputum analysis,none of which turns out to be effective in early diagnosis of lung cancer. Over the past several years various tumor biomarkers have [...]

Expression of Bmi-1 in NSCLC and Its Relationship to Clinicopathologic Characters

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Objective:To investigate the relationship between the expression of Bmi-1 in nonsmall-cell lung cancer(NSCLC) and clinicopathologic characters.Methods:Reverse transcription-PCR(RT-PCR)was applied to detect Bmi-1 mRNA in 30 of NSCLC speci-men and 20 of tumor-adjacent tissue.Immunohistochemistry was performed to detect the expression of Bmi-1 in 52 of NSCLC specimen and 30 of tumor-adjacent tissue.Results:The expression of Bmi-1mRNA in NSCLC [...]

Clinical analysis of Cyberknife stereotactic surgery for lung tumors

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Objective The aim of this study was to evaluate the safety and effectiveness of Cyberknife stereotactic surgery in the treatment of lung tumors by retrospectively analyzing the clinical results of the strategy.Methods Fifty patients,40 males and 10 females,and aged 19-90(means 68) years,were treated by Cyberknife stereotactic surgery for lung tumors,with real-time target tracking through fiducial [...]

Research of wogonin enchancing the sensitivity of A549 cells to TRAIL-induced apoptosis

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Objective To investigate the effect of wogonin on TRAIL-induced apoptosis in A549 cells. Methods A549 cells were cultured and treated with wogonin and/or TRAIL.Cell viability was determined by MTT assay.Apoptosis was detected by flow cytometry. Results The A549 cells were treated with IC50 doses of wogonin and/or 100 ng/mL TRAIL for 24 h,compared with cells [...]