OBJECTIVE:To investigate the efficacy,prognosis and predictive factor of neoadjurant chemotherapy with TEC regimen on node-positive and premenopausal breast cancer patients.METHODS:From June 01 2006 to June 01 2009,96 patients with premenopausal and node-positive breast cancer received TEC regimen neoadjuvant chemotherapy.The reaction rate of all patients was analyzed,and the predictive factors with stratification analysis according to the [...]
18
May
17
May
Analysis of acute kidney injury of primary liver cancer after TACE
Objective: To study the cause of acute kidney injury of primary liver cancer after TACE.Methods: Multivariate analysis of data of 286 patients with primary liver cancer who were treated by TACE.Results: Of 286 patients,23 patients had acute kidney injury after TACE.There was a closely correlation between acute kidney injury and age and basis diseases and [...]
17
May
Relationship between Expression of CD10 in Pancreatic Carcinoma and the Postoperative Survival
Objective To investigate the relationship between expression of CD10 in pancreatic carcinoma and their survival time after surgery.Methods Examined the expression status of CD10 in 83 cases of pancreatic carcinoma and 10 cases of normal pancreatic tissues samples by the method of immunohistochemical.The correlation among the variety of expression of CD10 and patients’ survival time [...]
17
May
Serum CEA level is associated with efficacy and prognosis of EGFR-TKI treatment in non-small cell lung cancer:report of 88 cases
Objective To identify the correlation of the serum carcinoembryonic antigen(CEA) level and the therapeutic effect of epidermal growth factor receptor tyrosine kinase inhibitor(EGFR-TKI) as a gene targeted drug in advanced non-small cell lung cancer(NSCLC).Methods We retrospectively reviewed 88 NSCLC patients,including 69 adenocarcinoma and 19 non-adenocarcinoma who admitted in our hospitals from July 2007 to November [...]
17
May
Influencing Factors of Primary Cytoreduction and Prognostic Factors in Advanced Epithelial Ovarian Cancer
Objective:To study the prognosis and factors affecting primary cytoreduction in advanced epithelial ovarian cancer.Methods:111 cases of advanced epithelial ovarian cancer admitted in our hospital for primary cytoreduction from 2003 to 2007 were retrospectively analyzed by SPSS11.5 software.Results:In advanced ovarian cancer 3-year survival rates and 5-year survival rates were 37.8% and 11.7% respectively.Univariate analysis showed that [...]
17
May
Correlation of Cyclin A1 Gene Hypermethylation in Promoter Region and Metastasis of Breast Carcinoma
Objective:To investigate the methylation pattern of CCNA1 in breast carcinoma and explore the role of these epige-netic changes in tumorgenensis.Methods:95 specimens of breast cancer were used,and the DNA was extracted by Qiagen procedure.Methylation change in the promoter region of CCNA1 was determined by using restricted enzyme cut-PCR.Results:The positive rate of gene promoter hypermethylation of CCNA1 [...]
17
May
17
May
The clinical correlation between prognosis of NSCLC and its serum tumor marker changes of pre-operation and post-operation
Objective To explore the correlation between serum tumor marker levels of CEA,NSE and CYFRA21-1 with therapeutic response of patients with lung cancer.Methods Serum specimens from 57 lung cancer patients were examined according to electrical chemiluminescent immunoassay before and after operation and the patients were followed up for 2 years.Results In 57 lung cancer patients,the overall [...]
17
May
17
May
Evaluation of factors related to prognosis and postoperative recurrence of gastric cancer
Objective To investigate the regular patterns of postoperative recurrence of gastric cancer and evaluate the indicators of long-term prognosis.Methods A total of 447 patients who underwent gastric cancer operation over a period of 25 years and had recurrece were divided into 2 groups: <2 years and 2-5 years,in accordance with the interval time of recurrence [...]