Objective To investigate the effects of 125I radioactive seeds combined with adriamycin(ADM) on proliferation and apoptosis of breast cancer MCF-7 cells in vitro.Methods The cultured breast cancer MCF-7 cells were randomly divided into four groups by 2×2 factorial design: 125I group,ADM group,125I combined with ADM group and control group.Cell cycle distribution and apoptosis of MCF-7 [...]
18
May
18
May
Studies on Mechanism of Lung Cancer by TCM Physique Study and Modern Medicine
The study of TCM constitution theory has made significant progress after the long period of development.Judging from the tumor,it is closely related to the pathogenesis of human body physique condition,and the development of physical biased is the important factor of tumor.The authors proposed by the constitution of TCM syndrome occurrence and development of tumor,combining modern [...]
17
May
Tubeimoside 1 enhances chemosensitivity of drug-resistant ovarian cancer A2780/DDP cells to cisplatin
Objective To determine the effect of tubeimoside 1(TBMS1) in enhancing chemosensitivity of drug-resistant ovarian cancer cell line(A2780/DDP) to cisplatin.MethodsThe A2780/DDP cells were treated with different concentrations of cisplatin and TBMS1 to analyze 50% inhibiting concentration(IC50) by methyl thiazolyl tetrazolium(MTT) assay.Experiment was divided into 4 groups.Control group:treatment with physiological saline;cisplatin group:treatment with 6 μmol/L cisplatin;Combination of [...]
17
May
17
May
The role of ING3 gene in human tumor research
The inhibitors of growth(ING) family(ING1-5),which are considered as type 2 tumor suppressors,are involved in the regulation of various processes ranging from cell growth,proliferation,cell cycle and cellular senescence to apoptosis.The ING3 gene,a novel number of the ING family,mapped to 7q31.3,is widely expressed in normal human tissues.However,loss or down regulation of ING3 expression is observed in most [...]
17
May
Programmed cell death and cancer
Programmed cell death(PCD) is genetically regulated cell death,involving a series of gene activation,expression and regulation.Currently,the classical apoptosis is considered as type Ⅰ PCD,whereas autophagic cell death is type Ⅱ PCD,necrosis-like programmed cell death is Ⅲ PCD.These modes of cell death play important roles in tumorigenesis,development,and therapeutics.With the most frontier studies in the field,this review mainly [...]
16
May
16
May
Harmonious coexistence and human tumor coexisting
Chinese medicine treatment of people-oriented,support healthy,conditioning organs,to people tumor balanced with tumor of survival status,improve patient quality of life and prolong survival time.
16
May
Expression and Implication of VEGF in Ovarian Cancer
Objective To study the relationship of vascular endothelial growth factor(VEGF) expression level and the clinical stages in ovarian cancer.Methods Thirty-three patients with ovarian cancer were enrolled as the experiment group and nine patients with normal uterine endometria were taken as the control group.Immunohistochemistry was used to detect the VEGF levels in the two groups.Results The [...]
16
May
Advance in research between MicroRNA and bladder cancer
microRNAs(miRNAs) are a class of small RNA molecules that regulate gene expression at the post-transcriptional level.Current studies have shown that miRNAs,which act as oncogenes or tumor suppressors,are directly involved in the formation and development of many kinds of human tumors.The aim of this review was to describe the formation and mechanism of miRNA,its relationship with [...]